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UltraClear Renew

UltraClear RENEW™

Medical Food

Brand: Metagenics

UltraClear RENEW, provided as a powdered beverage mix, is a medical food formulated to provide specialized nutritional support for patients with fibromyalgia and is designed for those who may benefit from additional nutritional support for hepatic detoxification function.


  • Helps to address altered pain signaling and neuromuscular function associated with fibromyalgia.
  • Features a proprietary spent hops powder and extracts of prune, pomegranate, and watercress.
  • Preliminary laboratory research suggests that spent hops may induce the expression of metallothionein, an antioxidant protein associated with the body?s detoxification of some heavy metals.
  • Preliminary laboratory work suggests that spent hops and prune extract may promote the activity of quinone reductase, a Phase II detoxification enzyme.
  • Preliminary laboratory research suggests that pomegranate extract may increase the activity of glutathione-S-transferase (GST), an important Phase II detoxification enzyme.
  • Provides glycine to support Phase II glycine conjugation, along with sulfate and L-cysteine to support Phase II sulfation.
  • Supplies green tea catechins and mixed carotenoids to protect against reactive species generated during hepatic detoxification.
  • Provides zinc, which some research suggests may help reduce oxidative stress associated with the metabolism and detoxification of heavy metals by beneficially influencing the activity and genetic expression of metallothionein.
  • In preliminary research†, UltraClear RENEW and a modified elimination diet was associated with a decrease in FibroQuest total score (pain and stiffness score) and an increase in excretion of certain heavy metals (such as mercury).
  • Comes with a Quick-Start Guide or a more comprehensive Patient Guide for complete program guidelines.

† In a preliminary study with a small number of fibromyalgia patients with dental amalgams conducted at the Functional Medicine Research CenterSM, the clinical research arm of Metagenics.

Serving Size: About 2 scoops (40 g)
Nutritional information per serving:
Calories  130 
Total Fat  3 g
  Saturated Fat††  1 g
  Trans Fat  0 g
Cholesterol  0 mg
Sodium (as sodium chloride)  220 mg
Potassium (as potassium citrate, dipotassium phosphate, and potassium iodide)  520 mg
Carbohydrate  20 g
  Dietary Fiber  3 g
  Sugars  6 g
Protein  12 g
Each Serving Contains:
Vitamin A (as beta-carotene)  4000 IU
Vitamin A (as retinyl palmitate)  1000 IU
Vitamin C (as ascorbic acid)  300 mg
Calcium (as calcium citrate)  150 mg
Iron  1 mg
Vitamin D (as cholecalciferol)  35 IU
Vitamin E (as d-alpha tocopheryl acetate)  42 IU
Thiamin (as thiamin HCl)  2 mg
Riboflavin  2 mg
Niacin (as niacinamide)  7 mg
Vitamin B6 (as pyridoxine HCl)  3.4 mg
Folate (as folic acid)  80 mcg
Vitamin B12 (as cyanocobalamin)  3.6 mcg
Biotin  135 mcg
Pantothenic acid (as D-calcium pantothenate)  36 mg
Phosphorus  230 mg
Iodine (as potassium iodide)  53 mcg
Magnesium (as magnesium citrate, magnesium chloride, and magnesium sulfate)  160 mg
Zinc (as zinc gluconate)  10 mg
Copper (as copper gluconate)  1 mg
Manganese  1 mg
Chromium (as chromium polynicotinate)  50 mcg
Proprietary Spent Hops (Humulus lupulus) Powder  1000 mg
L-Glycine  800 mg
Prune (Prunus domestica) Skin Extract  125 mg
L-Glutamine  100 mg
Watercress (Nasturtium officinale) Whole Plant Extract  67 mg
Ellagic Acid [from pomegranate (Punica granatum) Whole Fruit Extract]  50 mg
DL-Methionine  50 mg
L-Threonine  35 mg
L-Lysine (as L-lysine HCl)  35 mg
Sulfate (magnesium sulfate)  20 mg
L-Cysteine (as L-cysteine HCl)  15 mg
Catechins (from decaffeinated green tea extract)  15 mg
Other Ingredients: Rice protein concentrate, rice syrup solids, fructose, natural flavors, partially hydrolyzed guar gum, olive oil, medium chain triglycerides, cellulose gum, and silica.   
Recommendations: Blend, shake, or briskly stir about 2 level scoops (40 grams) of UltraClear RENEW into 8 ounces of chilled water or juice twice daily or as directed by your healthcare practitioner. For highly sensitive individuals, consider reducing consumption to 1/2 to 1 scoop with 4 to 5 ounces of chilled water or juice twice daily during the first 3 to 4 days before starting a full daily dose.

NOTICE: This product is to be used under the direct supervision of a physician or other licensed healthcare practitioner. Do not engage in any diet supplying less than 800 calories per day without medical supervision.

CAUTION: Do not use if pregnant or nursing. Not recommended for individuals taking anticoagulant medications.

††Saturated fat content is contributed by a beneficial form of fat, medium chain triglycerides, which have recognized health benefits.

UltraClear RENEW, provided as a powdered beverage mix, is a medical food formulated to provide specialized nutritional support for patients with fibromyalgia and is designed for those who ma
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